Tg(Hspa2-cre)1Eddy
Transgene Detail
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| Nomenclature |
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Symbol:
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Tg(Hspa2-cre)1Eddy
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Name:
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transgene insertion 1, Edward M Eddy
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MGI ID: |
MGI:3843498 |
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Synonyms: |
Hspa2-cre, Hspa2-cre line 54 |
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Transgene:
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Tg(Hspa2-cre)1Eddy
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: The Hspa2-Cre transgene was designed with (from 5' to 3') a 53 bp mouse Acrv1 (acrosomal vesicle protein 1 [SP-10]) insulator element, a promoter element from the mouse Hspa2 locus (heat shock protein 2 [Hsp70-2]); containing the ATG start site and 892 bp of immediately upstream sequence), a 275 bp fragment of the cre gene, the bovine growth hormone 3' UTR and polyA sequence, and another 53 bp mouse Acrv1 insulator element. This transgene was injected into C57BL/6 pronuclear stage embryos. Expression of Cre recombinase is directed to the developing male germ cells. (J:148085, J:156314)
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Recombinase activity
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Activity in:
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adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
cavities & their linings,
embryo-other,
endocrine system,
hemolymphoid system,
integumental system,
limbs,
liver & biliary system,
mesenchyme,
muscle,
nervous system,
renal & urinary system,
reproductive system,
respiratory system,
sensory organs,
skeletal system,
tail
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Not detected in:
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extraembryonic component
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Driver:
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Hspa2
Summary of all recombinase alleles
driven by Hspa2.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:156314
Inselman AL et al.,
"Heat shock protein 2 promoter drives cre expression in spermatocytes of transgenic mice."
Genesis 2010 Feb;48(2):114-20
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All: |
7 reference(s)
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Analysis Tools
