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| Nomenclature |
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Symbol:
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Tg(KRT5-Akt1*)Jmpa
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Name:
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transgene insertion, Jesus M Paramio
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MGI ID: |
MGI:3842829 |
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Synonyms: |
BK5myrAkt |
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Transgene:
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Tg(KRT5-Akt1*)Jmpa
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The bovine promoter was used to drive epithelial-specific expression of a myristoylated mouse Akt1. Two lines were created (L60 and L84). (J:127302)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:127302
Segrelles C et al.,
"Deregulated activity of Akt in epithelial basal cells induces spontaneous tumors and heightened sensitivity to skin carcinogenesis."
Cancer Res 2007 Nov 15;67(22):10879-88
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All: |
2 reference(s)
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Analysis Tools
