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| Nomenclature |
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Symbol:
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Tg(Myh6/tetO-PRKAG2*N488I)1Chib
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Name:
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transgene insertion 1, Charles I Berul
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MGI ID: |
MGI:3841177 |
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Transgene:
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Tg(Myh6/tetO-PRKAG2*N488I)1Chib
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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Not Specified
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A fusion promoter with tetO was used to drive repressible, cardiac expression of the human gene with an T to A substitution at position 1553 that results in the amino acid substitution of asparagine with isoleucine at position 488 (N488I). Thirteen lines were created with 2 exhibiting robust expression and phenotype. No line numbers were given. (J:145090)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:145090
Wolf CM et al.,
"Reversibility of PRKAG2 glycogen-storage cardiomyopathy and electrophysiological manifestations."
Circulation 2008 Jan 15;117(2):144-54
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All: |
1 reference(s)
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Analysis Tools
