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| Nomenclature |
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Symbol:
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Kdm3atm1.1Yzha
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Name:
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lysine (K)-specific demethylase 3A;
targeted mutation 1.1, Yi Zhang
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MGI ID: |
MGI:3840232 |
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Synonyms: |
Jhdm2a1loxP |
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Gene:
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Kdm3a
Location:
Chr6:71588974-71632905 bp, - strand
Genetic Position: Chr6,
32.18 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:147295
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 22 through 24 were removed by germ line, cre mediated recombination removing the catalytic jumonji C domain. The absence of protein expression was confirmed by western blot analysis on skeletal muscle extracts. (J:147295)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:147295
Tateishi K et al.,
"Role of Jhdm2a in regulating metabolic gene expression and obesity resistance."
Nature 2009 Apr 9;458(7239):757-61
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All: |
1 reference(s)
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