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| Nomenclature |
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Symbol:
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Tg(Scnn1a-cre)1Aibs
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Name:
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transgene insertion 1, Ed Lein
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MGI ID: |
MGI:3838497 |
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Synonyms: |
Scnna1-Tg1-Cre |
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Transgene:
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Tg(Scnn1a-cre)1Aibs
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x C3H)F1 x C57BL/6
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: The 196 kb C57BL/6J mouse bacterial artificial chromosome (BAC) RP23-405B24, containing the entire Scnn1a locus (and other genes), was modified by targeting a Cre recombinase coding sequence (the CreERT2 sequence modified back to encode the normal Cre recombinase gene), SV40 polyA signal, and frt-flanked neomycin cassette to the ATG start site of the Scnn1a locus. The targeted BAC sequences were further modified using FLP recombination to remove the selection cassette and linearized to remove its original vector backbone. Cre expression is directed to cortex, striatum, hippocampus and cerebellum by the Scnn1a promoter/enhancer regions within the BAC transgene. (J:146821)
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Recombinase activity
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Driver:
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Scnn1a
Summary of all recombinase alleles
driven by Scnn1a.
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MGI has not yet included tissue activity data for this allele in any anatomical systems.
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:146821
Allen Institute for Brain Science,
"Cre transgenes created at the Allen Insitute for Brain Science (AIBS)"
MGI Direct Data Submission 2009;():
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All: |
1 reference(s)
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Analysis Tools
