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| Nomenclature |
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Symbol:
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Tslptm1.1Pcn
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Name:
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thymic stromal lymphopoietin;
targeted mutation 1.1, Pierre Chambon
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MGI ID: |
MGI:3837749 |
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Synonyms: |
TslpL2 |
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Gene:
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Tslp
Location:
Chr18:32815383-32819799 bp, + strand
Genetic Position: Chr18,
18.12 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:146511
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 2 and an frt flanked neo cassette with a 5' loxP site was inserted downstream of exon 4. Germ line, flp mediated recombination was used to remove the neo cassette leaving exons 2 through 4 floxed. (J:146511)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Tslp Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:146511
Li M et al.,
"Induction of thymic stromal lymphopoietin expression in keratinocytes is necessary for generating an atopic dermatitis upon application of the active vitamin D3 analogue MC903 on mouse skin."
J Invest Dermatol 2009 Feb;129(2):498-502
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All: |
2 reference(s)
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