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| Nomenclature |
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Symbol:
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Tg(CSNK1D*)816Yfu
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Name:
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transgene insertion 816, Ying-Hui Fu
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MGI ID: |
MGI:3837569 |
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Synonyms: |
hCKIdelta-T44A L |
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Transgene:
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Tg(CSNK1D*)816Yfu
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x SJL)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The human BAC clone RP11-1376P16 containing the CSNK1D gene was targeted to generate a threonine-to-alanine mutation at amino acid 44 in the protein (T44A). An IRES-GFP cassette was also inserted after the stop codon of the CSNK1D gene. Six lines were generated with 4 of the lines 498, 503, 816 and 830, being low expressers due to insertion of only one copy of the transgene. Transgene expression was confirmed by RT-PCR of brain lysates. This is a representative record for the four low expressing lines. (J:97658)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:97658
Xu Y et al.,
"Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome."
Nature 2005 Mar 31;434(7033):640-4
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All: |
1 reference(s)
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Analysis Tools
