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| Nomenclature |
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Symbol:
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Tg(CSNK1D*)827Yfu
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Name:
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transgene insertion 827, Ying-Hui Fu
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MGI ID: |
MGI:3837566 |
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Synonyms: |
hCKIdelta-T44A H |
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Transgene:
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Tg(CSNK1D*)827Yfu
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x SJL)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The human BAC clone RP11-1376P16 containing the CSNK1D gene was targeted to generate a threonine-to-alanine alteration at amino acid 44 in the protein (T44A). An IRES-GFP cassette was also inserted after the stop codon of the CSNK1D gene. Six lines were generated with two of the lines, 827 and 859, being high expressers due to insertion of 2 to 3 copies of the transgene. Transgene expression was confirmed by RT-PCR of brain lysates. This is a representative record for the two high expressing lines. (J:97658)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:97658
Xu Y et al.,
"Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome."
Nature 2005 Mar 31;434(7033):640-4
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All: |
1 reference(s)
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Analysis Tools
