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| Nomenclature |
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Symbol:
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Tg(Ly6a-BCR/ABL1)IS1AIsg
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Name:
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transgene insertion IS1A, Isidro Sanchez-Garcia
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MGI ID: |
MGI:3834461 |
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Synonyms: |
IS1A |
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Transgene:
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Tg(Ly6a-BCR/ABL1)IS1AIsg
Location:
unknown
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Transgene origin |
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Strain of Origin:
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(CBA x C57BL/6J)
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Transgene description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The promoter was used to drive hematopoietic stem cell-specific expression of a human BCR-ABL1p210 fusion. Two lines were created (IS1A and IS1B) that exhibit similar phenotypes. (J:144382)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:144382
Perez-Caro M et al.,
"Cancer induction by restriction of oncogene expression to the stem cell compartment."
EMBO J 2009 Jan 7;28(1):8-20
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All: |
1 reference(s)
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