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| Nomenclature |
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Symbol:
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Gng7tm2(cre/PGR)Mmsh
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Name:
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guanine nucleotide binding protein (G protein), gamma 7;
targeted mutation 2, Masayoshi Mishina
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MGI ID: |
MGI:3833956 |
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Synonyms: |
Gng7mCrePR |
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Gene:
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Gng7
Location:
Chr10:80948624-81014945 bp, - strand
Genetic Position: Chr10,
39.72 cM
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Ablation of medium-spiny projection neurons in the striatum of Gng7tm2(cre/PGR)Mmsh/Gng7+ Eno2tm1(DTA)Hsak/Eno2+ mice
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:145152
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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C57BL/6
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: An inducible cre cassette consisting of mammalian optimized cre fused to the human progesterone receptor followed by a neo selection cassette in the inverse orientation were inserted into the translation initiation site via homologous recombination. Following RU-496 treatment no Cre activity was detected in brain slices. (J:145152)
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Recombinase activity
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Driver:
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Gng7
Summary of all recombinase alleles
driven by Gng7.
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MGI has not yet included tissue activity data for this allele in any anatomical systems.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gng7 Mutation:
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63 strains or lines available |
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| References |
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Original: |
J:145152
Kishioka A et al.,
"A novel form of memory for auditory fear conditioning at a low-intensity unconditioned stimulus."
PLoS ONE 2009;4(1):e4157
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All: |
1 reference(s)
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Analysis Tools
