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| Nomenclature |
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Symbol:
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Tg(CMV-TOR1A*)1Nush
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Name:
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transgene insertion 1, Nutan Sharma
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MGI ID: |
MGI:3832950 |
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Synonyms: |
hMT1 |
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Transgene:
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Tg(CMV-TOR1A*)1Nush
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x C3H)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The promoter was used to drive ubiquitous expression of a human cDNA containing a 3 bp deletion (delta GAG) identified in patients with DYT1 dystonia. Two lines were created (hMT1 and hMT2) with a 2-fold and 1.2-fold increase in expression levels, respectively.
(J:98716)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:98716
Sharma N et al.,
"Impaired motor learning in mice expressing torsinA with the DYT1 dystonia mutation."
J Neurosci 2005 Jun 1;25(22):5351-5
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All: |
7 reference(s)
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Analysis Tools
