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| Nomenclature |
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Symbol:
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Tg(Ela2a-Prss1*,GFP)1Dbs
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Name:
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transgene insertion 1, Dafna Bar-Sagi
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MGI ID: |
MGI:3832840 |
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Synonyms: |
R122H_mPRSS1 |
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Transgene:
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Tg(Ela2a-Prss1*,GFP)1Dbs
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The rat promoter was used to drive acinar cell-specific expression of a flag-tagged cDNA with nucleotide substitutions that result in the amino acid substitution of histidine for arginine at position 122 (R122H) and an IRES-GFP reporter. Three lines were made with copy numbers of the transgene ranging from ten (in two of three lines) to low numbers (in one line). No line numbers were given. (J:144663)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:144663
Archer H et al.,
"A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen."
Gastroenterology 2006 Dec;131(6):1844-55
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All: |
1 reference(s)
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Analysis Tools
