|
|
| Nomenclature |
|
Symbol:
|
Tg(Amhr2-Pik3ca*,-GFP)#Lzh
|
|
Name:
|
transgene insertion, Lin Zhang
|
|
MGI ID: |
MGI:3832594 |
|
Synonyms: |
PIK3CA-Tg |
|
Transgene:
|
Tg(Amhr2-Pik3ca*,-GFP)#Lzh
Location:
unknown
|
|
Tg(Amhr2-Pik3ca*,-GFP)#Lzh/0 females exhibit ovarian surface epithelium hyperplasia
Show the 1 image(s) involving this allele.
|
 |
|
Transgene
origin |
|
Strain of Origin:
|
(C57BL/6 x C3H)F1
|
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: This transgene consists of the mouse Amhr2 promoter driving expression of a constitutively active form of mouse Pik3ca and, following an IRES, GFP. The constitutively active form of Pik3ca was created by the addition of the avian src myristoylation sequence (MGSSKSKPK) to the N terminus of Pik3ca. Twelve founders were generated. This record represents pooled data from multiple founder lines. (J:144834)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
| References |
|
Original: |
J:144834
Liang S et al.,
"Expression of activated PIK3CA in ovarian surface epithelium results in hyperplasia but not tumor formation."
PLoS ONE 2009;4(1):e4295
|
|
All: |
1 reference(s)
|
|
Analysis Tools
