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| Nomenclature |
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Symbol:
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Prlhtm1Taon
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Name:
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prolactin releasing hormone;
targeted mutation 1, Tatsushi Onaka
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MGI ID: |
MGI:3832409 |
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Gene:
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Prlh
Location:
Chr1:90953108-90954012 bp, + strand
Genetic Position: Chr1,
45.81 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:144729
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Parent Cell Line:
| RW-4 (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: A 2 kb fragment including both exons 1 and 2 was replaced with a neo cassette via homologous recombination. RT-PCR and radioimmunoassay confirm the absence of RNA and protein expression in the hypothalamus and medulla oblongata of homozygous mice. (J:144729)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Prlh Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:144729
Takayanagi Y et al.,
"Endogenous prolactin-releasing peptide regulates food intake in rodents."
J Clin Invest 2008 Dec;118(12):4014-24
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All: |
1 reference(s)
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Analysis Tools
