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| Nomenclature |
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Symbol:
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Ldb3tm4Chen
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Name:
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LIM domain binding 3;
targeted mutation 4, Ju Chen
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MGI ID: |
MGI:3832388 |
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Synonyms: |
Cypherf |
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Gene:
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Ldb3
Location:
Chr14:34526699-34588681 bp, - strand
Genetic Position: Chr14,
20.83 cM, cytoband B
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:144739
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exon 1 was flanked with loxP sites and an frt flanked neo cassette was inserted after the second loxP site via homologous recombination. The neo cassette was then removed by Flp mediated recombination. (J:144739)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ldb3 Mutation:
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11 strains or lines available |
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| References |
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Original: |
J:144739
Zheng M et al.,
"Cardiac-specific ablation of Cypher leads to a severe form of dilated cardiomyopathy with premature death."
Hum Mol Genet 2009 Feb 15;18(4):701-13
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All: |
1 reference(s)
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Analysis Tools
