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| Nomenclature |
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Symbol:
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En2tm6Alj
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Name:
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engrailed 2;
targeted mutation 6, Alexandra L Joyner
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MGI ID: |
MGI:3831084 |
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Synonyms: |
En2flox, En2lox |
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Gene:
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En2
Location:
Chr5:28165696-28173612 bp, + strand
Genetic Position: Chr5,
13.94 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:156169
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Parent Cell Line:
| W4 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: The targeting construct contains a 3.1 kb En2 5' fragment, an Frt-flanked PGK-neo cassette followed by a LoxP site in the En2 intron and a 4.8 kb En2 genomic fragment containing a LoxP site in the XbaI site of the 3' UTR. Flpe-mediated recombination deleted the PGK-neo, producing an En2 allele with a floxed region. (J:156169)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:156169
Cheng Y et al.,
"The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum."
Development 2010 Feb;137(3):519-29
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All: |
3 reference(s)
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Analysis Tools
