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| Nomenclature |
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Symbol:
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Fermt1tm1Ref
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Name:
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fermitin family homolog 1 (Drosophila);
targeted mutation 1, Reinhard Fassler
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MGI ID: |
MGI:3828498 |
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Synonyms: |
Kindlin-1- |
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Gene:
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Fermt1
Location:
Chr2:132904389-132945906 bp, - strand
Genetic Position: Chr2,
64.8 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:142913
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 2 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on colonic intestional epithelial cell extracts. (J:142913)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Fermt1 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:142913
Ussar S et al.,
"Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction."
PLoS Genet 2008 Dec;4(12):e1000289
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All: |
1 reference(s)
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Analysis Tools
