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| Nomenclature |
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Symbol:
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Tg(Myh11-cre/ERT2)1Soff
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Name:
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transgene insertion 1, Stefan Offermanns
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MGI ID: |
MGI:3819270 |
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Synonyms: |
SMMHC-CreERT2, Tg(Myh11-cre/ESR1)1Soff |
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Transgene:
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Tg(Myh11-cre/ERT2)1Soff
Location:
unknown
Genetic Position: ChrY,
Syntenic
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: The mouse promoter from BAC clone 26630 was used to drive inducible cre expression in smooth muscle cells. An frt-flanked beta-lactamase gene contained within the cre/ESR1 cassette was removed by flp mediated recombination prior to micro-injection into fertilized oocytes. No line information was given.
(J:141641, J:148424)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:141641
Wirth A et al.,
"G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension."
Nat Med 2008 Jan;14(1):64-8
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All: |
14 reference(s)
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Analysis Tools
