|
|
| Nomenclature |
|
Symbol:
|
Tg(Ins-Igf2)1Fbos
|
|
Name:
|
transgene insertion 1, Fatima Bosch
|
|
MGI ID: |
MGI:3818739 |
|
Synonyms: |
RIPI/IGF-II |
|
Transgene:
|
Tg(Ins-Igf2)1Fbos
Location:
unknown
|
|
Transgene origin |
|
Strain of Origin:
|
C57BL/6 x SJL
|
|
Transgene description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The rat promoter was used to drive islet-specific expression of the mouse gene. Three lines were created (lines 1, 2 and 3) with similar phenotype. Line 1 was chosen as the representative line and has 40 copies of the transgene. (J:141527)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
| References |
|
Original: |
J:141527
Devedjian JC et al.,
"Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes."
J Clin Invest 2000 Mar;105(6):731-40
|
|
All: |
4 reference(s)
|
|