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| Nomenclature |
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Symbol:
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Gt(ROSA)26Sortm1(Crh)Jde
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Name:
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gene trap ROSA 26, Philippe Soriano;
targeted mutation 1, Jan Deussing
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MGI ID: |
MGI:3815322 |
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Synonyms: |
CRH-COE, R26flopCrh |
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Gene:
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Gt(ROSA)26Sor
Location:
Chr6:113067428-113077333 bp, - strand
Genetic Position: Chr6,
52.73 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:149207
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Parent Cell Line:
| TBV2 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Coding sequence for murine Crh gene was preceded by a loxP-flanked transcriptional terminator and then was knocked into the Gt(ROSA)26Sor locus. Upon cre recombinase expression and excision of the loxP-stop sequence, the Crh gene is predicted to be expressed. (J:149207)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gt(ROSA)26Sor Mutation:
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191 strains or lines available |
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| References |
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Original: |
J:149207
Lu A et al.,
"Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior."
Mol Psychiatry 2008 Nov;13(11):1028-42
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All: |
5 reference(s)
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Analysis Tools
