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Hspa5tm1Alee
Targeted Allele Detail

Nomenclature
Symbol: Hspa5tm1Alee
Name: heat shock protein 5; targeted mutation 1, Amy S Lee
MGI ID: MGI:3814698
Synonyms: Grp78f, tri-loxP
Gene: Hspa5   Location: Chr2:34771970-34776531 bp, + strand    Genetic Position: Chr2, 22.94 cM
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:111416
Parent Cell Line: Not Specified (ES Cell)
Strain of Origin: 129
Mutation
description
Allele Type:   Targeted (Floxed/Frt)
Mutation:   Insertion
    A vector was designed to insert a floxed neo into intron 4 and a third loxP site into intron 7. (J:111416)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hspa5 Mutation: 5 strains or lines available
References
Original: J:111416 Luo S et al., "GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development." Mol Cell Biol 2006 Aug;26(15):5688-97
All: 4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory