|
|
| Nomenclature |
|
Symbol:
|
Tg(Ppp1r1b-HTT*)1Meeh
|
|
Name:
|
transgene insertion 1, Michelle E Erlich
|
|
MGI ID: |
MGI:3813481 |
|
Synonyms: |
D9-N171-98Q, DE5 |
|
Transgene:
|
Tg(Ppp1r1b-HTT*)1Meeh
Location:
unknown
|
|
Transgene
origin |
|
Strain of Origin:
|
C57BL/6J
|
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: A 9 kb genomic fragment containing mouse Ppp1r1b was used to drive expression of an IRES fused cDNA for human HTT that encodes for the first 171 amino acids with an expanded CAG repeat of 98 nucleotides in length in the medium spiny neurons of the striatum. No line information is available.
(J:139807)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
| References |
|
Original: |
J:139807
Brown TB et al.,
"Neocortical expression of mutant huntingtin is not required for alterations in striatal gene expression or motor dysfunction in a transgenic mouse."
Hum Mol Genet 2008 Oct 15;17(20):3095-104
|
|
All: |
2 reference(s)
|
|
Analysis Tools
