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| Nomenclature |
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Symbol:
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Tg(CAG-lacZ,-Akt1*,-EGFP)56Ebm
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Name:
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transgene insertion 56, Ernesto Bernal-Mizrachi
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MGI ID: |
MGI:3811006 |
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Synonyms: |
LSL-myr-Akt, pCALL2-caAkt |
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Transgene:
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Tg(CAG-lacZ,-Akt1*,-EGFP)56Ebm
Location:
unknown
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Transgene
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:136227
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene consists of a chicken beta-actin promoter with the upstream cytomegalovirus enhancer (pCAGGS) followed by a floxed lacZ neo fusion cassette with three SV40 poladenylation sites, a constitutively active form of Akt1 with an HA epitope, an IRES site, and enhanced GFP. Cre-mediated recombination allows for expression of the constitutively active Akt1 and EGFP. Two lines were generated (42 and 56) that both had strong homogeneous lacZ expression. This is a representative record for these two lines. (J:136227)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:136227
Elghazi L et al.,
"Generation of a reporter mouse line expressing Akt and EGFP upon Cre-mediated recombination."
Genesis 2008 May;46(5):256-64
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All: |
4 reference(s)
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Analysis Tools
