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| Nomenclature |
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Symbol:
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Tg(tetO-MET)23Rwng
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Name:
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transgene insertion 23, Rong Wang
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MGI ID: |
MGI:3810467 |
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Synonyms: |
TRE-hMET, TRE-MET |
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Transgene:
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Tg(tetO-MET)23Rwng
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The TRE-MET transgene was designed with the human MET (met proto-oncogene (hepatocyte growth factor receptor)) coding sequence, under the control of heptamerized tetracycline operator (tetO; also called tetracycline-responsive element (TRE) or tet-operator) sequences and a cytomegalovirus (hCMV) minimal promoter with a beta-globin poly A signal. Founder line 23 was subsequently established. (J:69731)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:69731
Wang R et al.,
"Activation of the met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice."
J Cell Biol 2001 May 28;153(5):1023-34
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All: |
4 reference(s)
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Analysis Tools
