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| Nomenclature |
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Symbol:
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Olig2tm2(TVA,cre)Rth
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Name:
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oligodendrocyte transcription factor 2;
targeted mutation 2, David H Rowitch
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MGI ID: |
MGI:3810299 |
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Synonyms: |
Olig2-tva-cre |
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Gene:
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Olig2
Location:
Chr16:91225550-91228677 bp, + strand
Genetic Position: Chr16,
52.6 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:139574
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A cDNA encoding the avian specific retroviral receptor (TVA) followed by an IRES-cre and neo cassette was inserted immediately downstream of the translation initiation site. (J:139574)
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Recombinase activity
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Driver:
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Olig2
Summary of all recombinase alleles
driven by Olig2.
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MGI has not yet included tissue activity data for this allele in any anatomical systems.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:139574
Schuller U et al.,
"Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma."
Cancer Cell 2008 Aug 12;14(2):123-34
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All: |
10 reference(s)
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Analysis Tools
