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| Nomenclature |
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Symbol:
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Hes1tm1Kag
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Name:
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hairy and enhancer of split 1 (Drosophila);
targeted mutation 1, Ryoichiro Kageyama
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MGI ID: |
MGI:3808031 |
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Synonyms: |
Hes1f |
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Gene:
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Hes1
Location:
Chr16:30064384-30067796 bp, + strand
Genetic Position: Chr16,
21.09 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:139170
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Parent Cell Line:
| TT2 (ES Cell) |
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Strain of Origin:
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(C57BL/6NCrlj x CBA/JNCrlj)F1
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted after the first coding exon and a floxed neo cassette was inserted after the last coding exon. Expression of cre in ES cells was used to remove the neo cssette leaving coding exons 2 through 4 floxed. (J:139170)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Hes1 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:139170
Imayoshi I et al.,
"Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline."
Development 2008 Aug;135(15):2531-41
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All: |
13 reference(s)
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Analysis Tools
