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| Nomenclature |
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Symbol:
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Hmx1mpe
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Name:
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H6 homeobox 1;
misplaced ears
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MGI ID: |
MGI:3807082 |
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Gene:
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Hmx1
Location:
Chr5:35388858-35399730 bp, + strand
Genetic Position: Chr5,
18.14 cM
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Hmx1mpe/Hmx1mpe mouse
Show the 2 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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C3H/HeJ
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Intragenic deletion |
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Mutation details: An 8 base pair deletion in the region of exon 2, which encodes the homeodomain, results in a frameshift beginning at amino acid 226 that is predicted to replace the C-terminal 106 amino acids with an anomalous 171 amino acids. (J:147782)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:147782
Monroe RJ et al.,
"Mouse H6 Homeobox 1 (Hmx1) mutations cause cranial abnormalities and reduced body mass"
BMC Dev Biol 2009;9(1):27
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All: |
1 reference(s)
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Analysis Tools
