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| Nomenclature |
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Symbol:
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Tg(MC1R)1Jkn
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Name:
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transgene insertion 1, Ian J Jackson
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MGI ID: |
MGI:3805878 |
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Synonyms: |
Tg-MC1R |
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Transgene:
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Tg(MC1R)1Jkn
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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Not Specified
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The transgene strain was created by microinjection of the human BAC RPCI11-655K11 into embryos homozygous for Mc1re. The BAC contains 146 kb of sequence with the complete human gene MC1R and includes at least 4 other genes. Quantitative RT-PCR on skin samples indicated that expression of the human MC1R was 9- to 20-fold lower than the endogenous mouse gene. (J:129904)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:129904
Jackson IJ et al.,
"Humanized MC1R transgenic mice reveal human specific receptor function."
Hum Mol Genet 2007 Oct 1;16(19):2341-8
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All: |
1 reference(s)
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Analysis Tools
