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| Nomenclature |
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Symbol:
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Pik3cbtm1Jjz
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Name:
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phosphatidylinositol 3-kinase, catalytic, beta polypeptide;
targeted mutation 1, Jean Zhao
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MGI ID: |
MGI:3805847 |
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Synonyms: |
p110betaflox |
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Gene:
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Pik3cb
Location:
Chr9:99038402-99140621 bp, - strand
Genetic Position: Chr9,
51.41 cM, cytoband E4
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:138565
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S/SvEv
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: An frt-flanked neo cassette with a 5' loxP site was inserted upstream of exon 2 and an additional loxP site was inserted downstream of exon 2. Germ line, flp-mediated recombination was used to remove the neo cassette leaving exon 2 floxed. (J:138565)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:138565
Jia S et al.,
"Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis."
Nature 2008 Aug 7;454(7205):776-9
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All: |
3 reference(s)
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Analysis Tools
