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| Nomenclature |
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Symbol:
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Wnt9btm1.2Amc
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Name:
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wingless-type MMTV integration site 9B;
targeted mutation 1.2, Andrew P McMahon
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MGI ID: |
MGI:3805020 |
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Synonyms: |
Wnt9bc, Wnt9bflox |
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Gene:
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Wnt9b
Location:
Chr11:103727364-103749821 bp, - strand
Genetic Position: Chr11,
67.47 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:100575
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Parent Cell Line:
| AV3 (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A targeting vector was designed to insert a loxP site just upstream of exon 2, and a frt-flanked PGK-Neo cassette followed by a second loxP site just downstream of exon 2 of the targeted gene to generate Wnt9bMtm1Amc mice (Wnt9bcneo. To remove the frt-flanked selection cassette, these mice were then bred to an FLPe-expressing strain (on the Swiss-Webster genetic background). The resulting Wnt9bc offspring carry a loxP site just upstream of exon 2, and a single remaining frt-site followed by a second loxP site just downstream of exon 2. (J:100575)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:100575
Carroll TJ et al.,
"Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system."
Dev Cell 2005 Aug;9(2):283-92
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All: |
5 reference(s)
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Analysis Tools
