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| Nomenclature |
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Symbol:
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Mapk1tm1Gela
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Name:
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mitogen-activated protein kinase 1;
targeted mutation 1, Gary E Landreth
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MGI ID: |
MGI:3803954 |
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Synonyms: |
ERK2fl, Mapk1flox |
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Gene:
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Mapk1
Location:
Chr16:16983382-17047453 bp, + strand
Genetic Position: Chr16,
10.53 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:137882
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A floxed neo cassette was inserted upstream of exon 2 and an additional loxP site was inserted downstream of exon 2. Transient cre transfection into ES cells was used to remove the neo cassette leaving exon 2 floxed. (J:137882)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:137882
Samuels IS et al.,
"Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function."
J Neurosci 2008 Jul 2;28(27):6983-95
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All: |
9 reference(s)
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Analysis Tools
