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| Nomenclature |
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Symbol:
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Kat2atm3.2Roth
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Name:
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K(lysine) acetyltransferase 2A;
targeted mutation 3.2, Sharon Y R Dent
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MGI ID: |
MGI:3801276 |
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Synonyms: |
Gcn5flox |
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Gene:
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Kat2a
Location:
Chr11:100704746-100712465 bp, - strand
Genetic Position: Chr11,
63.53 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:132940
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129/Sv
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A floxed neo cassette was inserted downstream of exon 2 and an additional loxP site was inserted downstream of exon 18. Germ line, cre-mediated recombination was used to remove the neo cassette leaving exons 3 through 18 floxed. (J:132940)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Kat2a Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:132940
Lin W et al.,
"Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos."
Dev Dyn 2008 Apr;237(4):928-40
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All: |
6 reference(s)
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