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| Nomenclature |
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Symbol:
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Add1tm1Llp
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Name:
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adducin 1 (alpha);
targeted mutation 1, Luanne Peters
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MGI ID: |
MGI:3799499 |
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Gene:
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Add1
Location:
Chr5:34573664-34632308 bp, + strand
Genetic Position: Chr5,
17.9 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:138919
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: Exons 10, 11 and 12 and their intervening introns have been replaced by a neomycin resistance cassette.
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:138919
Robledo RF et al.,
"Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice."
Blood 2008 Nov 15;112(10):4298-307
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All: |
3 reference(s)
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Analysis Tools
