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| Nomenclature |
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Symbol:
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Gli3tm1Alj
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Name:
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GLI-Kruppel family member GLI3;
targeted mutation 1, Alexandra L Joyner
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MGI ID: |
MGI:3798847 |
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Synonyms: |
Gli3F, Gli3flox |
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Gene:
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Gli3
Location:
Chr13:15463235-15730026 bp, + strand
Genetic Position: Chr13,
5.43 cM, cytoband A2
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:137136
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Parent Cell Line:
| W4 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: An frt-flanked neo cassette with a 5' loxP site was inserted upstream of exon 8 and an additional loxP site was inserted downstream of exon 8. Germ line, flp-mediated recombination was used to remove the neo cassette leaving exon 8 floxed. (J:137136)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:137136
Blaess S et al.,
"Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling."
Development 2008 Jun;135(12):2093-103
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All: |
5 reference(s)
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Analysis Tools
