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| Nomenclature |
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Symbol:
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Opn4tm1(cre)Sapa
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Name:
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opsin 4 (melanopsin);
targeted mutation 1, Satchidananda Panda
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MGI ID: |
MGI:3798479 |
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Synonyms: |
Opn4Cre |
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Gene:
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Opn4
Location:
Chr14:34590618-34600142 bp, - strand
Genetic Position: Chr14,
20.83 cM, cytoband B
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:137151
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The first 7 exons were replaced with a cassette containing a cre gene, IRES/betaTau, a floxed neo and eYFP gene. No YFP expression was detected in the retina. Cre activity is detected in the retinal ganglion cell layer. (J:137151)
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Recombinase activity
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Driver:
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Opn4
Summary of all recombinase alleles
driven by Opn4.
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MGI has not yet included tissue activity data for this allele in any anatomical systems.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Opn4 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:137151
Hatori M et al.,
"Inducible ablation of melanopsin-expressing retinal ganglion cells reveals their central role in non-image forming visual responses."
PLoS ONE 2008;3(6):e2451
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All: |
4 reference(s)
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Analysis Tools
