|
|
| Nomenclature |
|
Symbol:
|
Del(5D5Mit388-D5Mit351)4Jcs
|
|
Name:
|
deletion, Chr 5, John C. Schimenti 4;
deletion, Chr 5, John C Schimenti 4
|
|
MGI ID: |
MGI:3798167 |
|
Synonyms: |
Del4Jcs, Hdhdf7J |
|
Gene:
|
Del(5D5Mit388-D5Mit351)4Jcs
Location:
unknown
Genetic Position: Chr5,
Syntenic
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:67077
|
|
Parent Cell Line:
| v6.4 (ES Cell) |
|
Strain of Origin:
|
(C57BL/6J x 129S4/SvJae)F1
|
|
Mutation
description |
|
Allele
Type: | |
Radiation induced |
|
Mutation: | |
Intergenic deletion |
| |
|
Mutation details: Targeted insertion of thymidine kinase into the C57BL/6J derived Chromosome 5 Htt locus in the v6.4 ES cell line was followed by 400 Gy of gamma radiation, FIAU selection, and injection into the C57BL/6J blastocysts. The deletion includes the full Wolf-Hurschhorn syndrome critical region. (J:67077)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Del(5D5Mit388-D5Mit351)4Jcs Mutation:
|
0 strains or lines available |
|
| References |
|
Original: |
J:67077
Naf D et al.,
"Mouse models for the Wolf-Hirschhorn deletion syndrome."
Hum Mol Genet 2001 Jan 15;10(2):91-8
|
|
All: |
2 reference(s)
|
|
Analysis Tools
