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| Nomenclature |
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Symbol:
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Sosttm1(KOMP)Vlcg
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Name:
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sclerostin;
targeted mutation 1, Velocigene
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MGI ID: |
MGI:3797839 |
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Synonyms: |
SostLacZ, Sosttm1Vlcg |
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Gene:
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Sost
Location:
Chr11:101962458-101967015 bp, - strand
Genetic Position: Chr11,
65.48 cM, cytoband D
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Mutation origin |
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Mutant Cell Lines:
| 10069A-G10, 10069B-C10, 10069B-C7, 10069B-E8 (Velocigene) |
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Germline Transmission:
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Earliest citation of germline transmission:
J:167585
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Parent Cell Line:
| VGB6 (ES Cell) |
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Strain of Origin:
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C57BL/6NTac
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion Vector: ZEN-Ub1 |
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Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 3174bp between positions 101825111-101828284 of Chromosome 11 (Genome Build37). (J:136110, J:167585)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:136110
Velocigene,
"Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)"
MGI Direct Data Submission 2008;():
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All: |
3 reference(s)
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