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| Nomenclature |
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Symbol:
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Slc17a8tm1Selm
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Name:
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solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8;
targeted mutation 1, Salah El Mestikawy
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MGI ID: |
MGI:3794893 |
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Synonyms: |
Vglut3- |
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Gene:
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Slc17a8
Location:
Chr10:89574020-89621253 bp, - strand
Genetic Position: Chr10,
44.99 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:135586
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129/Sv
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 2 was replaced with an frt-flanked neo cassette. This results in creation of a stop codon in exon3. The absence of protein product was confirmed by immunohistochemistry on brain sections. (J:135586, J:139493)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Slc17a8 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:135586
Gras C et al.,
"The vesicular glutamate transporter VGLUT3 synergizes striatal acetylcholine tone."
Nat Neurosci 2008 Mar;11(3):292-300
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All: |
3 reference(s)
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Analysis Tools
