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| Nomenclature |
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Symbol:
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Tg(LCR-HBA2,LCR-HBB)11Cos
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Name:
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transgene insertion 11, Frank Costantini
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MGI ID: |
MGI:3794861 |
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Synonyms: |
alphaHbetaS, NY1DD, NY-S |
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Transgene:
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Tg(LCR-HBA2,LCR-HBB)11Cos
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: Constructs expressing the human alpha globin 2 gene from the locus control region of the human beta globin gene and the human beta globin gene also from the human locus control region were coinjected to create a line of mice with cointegrated transgenes. Transgene expression is noted in red blood cells. (J:129579)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:129579
Fabry ME et al.,
"High expression of human beta S- and alpha-globins in transgenic mice: hemoglobin composition and hematological consequences."
Proc Natl Acad Sci U S A 1992 Dec 15;89(24):12150-4
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All: |
25 reference(s)
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Analysis Tools
