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| Nomenclature |
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Symbol:
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Akt1tm1Pnt
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Name:
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thymoma viral proto-oncogene 1;
targeted mutation 1, Philip N Tsichlis
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MGI ID: |
MGI:3794787 |
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Synonyms: |
Akt1fl |
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Gene:
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Akt1
Location:
Chr12:112653821-112674884 bp, - strand
Genetic Position: Chr12,
61.2 cM, cytoband F1-F2
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:135903
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A floxed neo cassette was inserted downstream of exon 2 and an additional loxP site was inserted downstream of exon 4. (J:135903)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Akt1 Mutation:
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8 strains or lines available |
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| References |
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Original: |
J:135903
Mao C et al.,
"Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition."
J Immunol 2007 May 1;178(9):5443-53
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All: |
4 reference(s)
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