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| Nomenclature |
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Symbol:
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Tg(Pbsn-TAg)15Tvd
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Name:
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transgene insertion 15, Terry Van Dyke
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MGI ID: |
MGI:3794201 |
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Synonyms: |
TgAPT121 |
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Transgene:
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Tg(Pbsn-TAg)15Tvd
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The 458pb ARR2PB promoter which is regulated by androgens and is activated during puberty was used to drive expression of the truncated SV40 large T antigen but not the small t antigen. The translation product contains the first 121 amino acids of SV40 T followed by 11 missense amino acids. (J:103408)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:103408
Hill R et al.,
"Heterogeneous tumor evolution initiated by loss of pRb function in a preclinical prostate cancer model."
Cancer Res 2005 Nov 15;65(22):10243-54
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All: |
4 reference(s)
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Analysis Tools
