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| Nomenclature |
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Symbol:
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Gt(ROSA)26Sortm1(RARA*)Soc
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Name:
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gene trap ROSA 26, Philippe Soriano;
targeted mutation 1, Shanthini Sockanathan
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MGI ID: |
MGI:3793772 |
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Synonyms: |
R26RAR403, Rara403 conditional |
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Gene:
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Gt(ROSA)26Sor
Location:
Chr6:113067428-113077333 bp, - strand
Genetic Position: Chr6,
52.73 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:135403
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A floxed neo-STOP cassette followed by a dominant negative form of human RARA (RAR403) was inserted into the ROSA locus. Cre mediated removal of the neo-STOP cassette is necessary for expression of RAR403. (J:135403)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gt(ROSA)26Sor Mutation:
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191 strains or lines available |
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| References |
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Original: |
J:135403
Rajaii F et al.,
"Expression of the dominant negative retinoid receptor, RAR403, alters telencephalic progenitor proliferation, survival, and cell fate specification."
Dev Biol 2008 Apr 15;316(2):371-82
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All: |
2 reference(s)
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