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| Nomenclature |
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Symbol:
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Lactb2Tg(Igh-Meis1)2770Amb
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Name:
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lactamase, beta 2;
transgene insertion 2770, Arthur M Buchberg
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MGI ID: |
MGI:3793472 |
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Synonyms: |
Tg2770 |
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Gene:
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Lactb2
Location:
Chr1:13624845-13660546 bp, - strand
Genetic Position: Chr1,
4.29 cM
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, gene disruption) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A transgene was constructed in which the Igh promoter and enhancers were used to drive expression of the Meis1 cDNA (transcript a). Sequencing of line 2770 revealed the integration site to be located within Lactb replacing a 21.3 kb segment containing exons 5 through 7. (J:79618)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Lactb2 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:79618
Sollars VE et al.,
"A novel transgenic line of mice exhibiting autosomal recessive male-specific lethality and non-alcoholic fatty liver disease."
Hum Mol Genet 2002 Nov 1;11(22):2777-86
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All: |
1 reference(s)
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Analysis Tools
