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| Nomenclature |
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Symbol:
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Gp1bbtm2Frla
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Name:
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glycoprotein Ib, beta polypeptide;
targeted mutation 2, Francois Lanza
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MGI ID: |
MGI:3793297 |
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Synonyms: |
GPIbbetadeltaIC |
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Gene:
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Gp1bb
Location:
Chr16:18620319-18622403 bp, - strand
Genetic Position: Chr16,
11.53 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:135065
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Parent Cell Line:
| P1 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A floxed neo cassette was inserted upstream of the coding region and the coding region was replaced with one in which the intracellular domain has been deleted. Cre mediated recombination was used to remove the neo cassette. (J:135065)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:135065
Strassel C et al.,
"Decreased thrombotic tendency in mouse models of the Bernard-Soulier syndrome."
Arterioscler Thromb Vasc Biol 2007 Jan;27(1):241-7
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All: |
1 reference(s)
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Analysis Tools
