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| Nomenclature |
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Symbol:
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Gp1bbtm1Frla
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Name:
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glycoprotein Ib, beta polypeptide;
targeted mutation 1, Francois Lanza
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MGI ID: |
MGI:3793296 |
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Synonyms: |
GPIbbeta- |
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Gene:
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Gp1bb
Location:
Chr16:18620319-18622403 bp, - strand
Genetic Position: Chr16,
11.53 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:135065
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Parent Cell Line:
| P1 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The entire coding region was replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis on platelet extracts. (J:135065)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:135065
Strassel C et al.,
"Decreased thrombotic tendency in mouse models of the Bernard-Soulier syndrome."
Arterioscler Thromb Vasc Biol 2007 Jan;27(1):241-7
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All: |
2 reference(s)
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Analysis Tools
