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| Nomenclature |
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Symbol:
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Tlx3tm1(cre)Qima
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Name:
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T cell leukemia, homeobox 3;
targeted mutation 1, Qiufu Ma
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MGI ID: |
MGI:3789185 |
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Synonyms: |
Tlx3Cre |
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Gene:
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Tlx3
Location:
Chr11:33200752-33203588 bp, - strand
Genetic Position: Chr11,
19.21 cM, cytoband A5
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:134327
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A cre cassette followed by an frt-flanked neo was inserted into exon 2. Germ-line, flp-mediated recombination was used to remove the neo cassette. Cre expression recapitulates endogenous promoter activity. (J:134327)
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Recombinase activity
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Driver:
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Tlx3
Summary of all recombinase alleles
driven by Tlx3.
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MGI has not yet included tissue activity data for this allele in any anatomical systems.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Tlx3 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:134327
Xu Y et al.,
"Tlx1 and Tlx3 coordinate specification of dorsal horn pain-modulatory peptidergic neurons."
J Neurosci 2008 Apr 9;28(15):4037-46
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All: |
4 reference(s)
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Analysis Tools
