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| Nomenclature |
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Symbol:
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Tg(Cma1-cre)ARoer
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Name:
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transgene insertion A, Axel Roers
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MGI ID: |
MGI:3785000 |
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Synonyms: |
A-Mcpt5-Cre, TgMcpt5-Cre |
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Transgene:
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Tg(Cma1-cre)ARoer
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: This transgene contains a modified BAC RP23-284A14 in which a cre and floxed neo cassette was inserted into exon 1 replacing a portion of the coding region. Cre-mediated deletion was used to remove the neo cassette. Six founder lines were generated one with only 80% of peritoneal mast cells expressing the transgene that was not further examined and two other lines expressing in 100% of peritoneal cells in an autosomal inheritance pattern (line A) and the other in an X-linked inheritance pattern (line X). (J:133910)
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Recombinase activity
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Driver:
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Cma1
Summary of all recombinase alleles
driven by Cma1.
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MGI has not yet included tissue activity data for this allele in any anatomical systems.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:133910
Scholten J et al.,
"Mast cell-specific Cre/loxP-mediated recombination in vivo."
Transgenic Res 2008 Apr;17(2):307-15
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All: |
6 reference(s)
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Analysis Tools
