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| Nomenclature |
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Symbol:
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Pbx1tm2.1Mlc
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Name:
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pre B cell leukemia homeobox 1;
targeted mutation 2.1, Micheal L Cleary
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MGI ID: |
MGI:3783740 |
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Gene:
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Pbx1
Location:
Chr1:168153527-168432270 bp, - strand
Genetic Position: Chr1,
75.95 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:132963
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Parent Cell Line:
| TL1/TL-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: Cre mediated recombination of Pbx1tm2Mlc resulted in deletion of exon 3. (J:132963)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pbx1 Mutation:
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19 strains or lines available |
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| References |
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Original: |
J:132963
Sanyal M et al.,
"B-cell development fails in the absence of the Pbx1 proto-oncogene."
Blood 2007 May 15;109(10):4191-9
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All: |
1 reference(s)
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