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| Nomenclature |
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Symbol:
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Mfn2tm3Dcc
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Name:
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mitofusin 2;
targeted mutation 3, David C Chan
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MGI ID: |
MGI:3779081 |
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Synonyms: |
Mfn2loxP |
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Gene:
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Mfn2
Location:
Chr4:147873599-147904704 bp, - strand
Genetic Position: Chr4,
78.56 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:132329
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: FRT-flanked neo cassette followed by two loxP sites flanking the exon 6 encoding the canonical G-1 GTPase motif replaced the endogenous locus. The neo cassette was removed by crossing with FLP recombinase expressing mice. (J:132329)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:132329
Chen H et al.,
"Mitochondrial fusion protects against neurodegeneration in the cerebellum."
Cell 2007 Aug 10;130(3):548-62
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All: |
6 reference(s)
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Analysis Tools
