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| Nomenclature |
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Symbol:
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Grhl1tm1Jane
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Name:
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grainyhead-like 1 (Drosophila);
targeted mutation 1, Stephen M Jane
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MGI ID: |
MGI:3778923 |
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Gene:
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Grhl1
Location:
Chr12:24572287-24617391 bp, + strand
Genetic Position: Chr12,
8.49 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:133318
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 1 and 2 were replaced with a lacZ and floxed neo cassette. The neo cassette was subsequently removed by germ-line, cre-mediated recombination. The absence of transcript was confirmed by RT-PCR on brain, kidney, testis, lung, stomach, liver, spleen, thymus, heart, and skin extracts. This is a null allele. (J:133318)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Grhl1 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:133318
Wilanowski T et al.,
"Perturbed desmosomal cadherin expression in grainy head-like 1-null mice."
EMBO J 2008 Mar 19;27(6):886-97
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All: |
2 reference(s)
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Analysis Tools
